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Therapeutic Proteins Against Human Diseases

Posted By: AvaxGenius

Date: 2 Oct 2022 22:18:21

This book compiles updated research about the implications of therapeutic proteins in various human diseases. The initial chapters of the book provide basic information on the therapeutic proteins and discuss techniques for their formulation, production, and analytic approaches for their characterization. The subsequent chapters shed light on therapies based on therapeutic proteins against metabolic disorders, neurological disorders, cancer, autoimmune disorders, and infectious diseases. Importantly, it presents the factors influencing the immunogenicity of therapeutic proteins, including, genetic factors, disease type, and origin of therapeutic protein, dose frequency, administration route, and treatment duration.

Science medicinal chemistry drug discovery Therapeutics Diseases Pharmacology Medical Biochemistry Protein Biochemistry Medicine

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Drug Target Selection and Validation

Posted By: AvaxGenius

Date: 24 May 2022 22:11:35

The first book in the newly created book series, Computer-Aided Drug Discovery and Design, focuses on the computational aspects of early drug discovery, drug target identification, and validation. It revises current classical paradigms in target and phenotypic-based drug design with still ingrained approximations and concepts and discusses the research in the new network approach concept that include kinetic selectivity and metabolic analysis.

drug discovery druggability Science drug design metabolic analysis Pharmacology Pharmaceutics Drug Design Medicinal Chemistry Molecular Biology Biology

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Druggable Lipid Signaling Pathways

Posted By: AvaxGenius

Date: 7 Sep 2020 13:47:02

This edited work presents a series of reviews focusing on Druggable Lipid Signaling Pathways. It enables researchers in both academic institutions and industry as well as physicians to understand historical aspects of lipid signaling and future directions of drug discovery targeting lipid signaling pathways. This book provides 9 pathways including acyltransferases, prostanoids, leukotrienes, epoxy fatty acids, sphingolipids, lysophospholipids, endocannabinoids, phosphoinositides, and lipid GPCRs.

Biology Genetics Science translational research disease GPCR lipids Medicine drug discovery ePub

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Molecular Theory of the Living Cell: Concepts, Molecular Mechanisms, and Biomedical Applications

Posted By: AvaxGenius

Date: 17 Apr 2020 18:16:53

The book presents the first comprehensive molecular theory of the living cell ever published since the cell doctrine was formulated in 1838-1839. It introduces into cell biology over thirty key concepts, principles and laws imported from physics, chemistry, computer science, linguistics, semiotics and philosophy. The author formulates physically, chemically and enzymologically realistic molecular mechanisms to account for basic living processes such as ligand-receptor interactions, enzymic catalysis, force-generating mechanisms in molecular motors, chromatin remodelling, and signal transduction. Possible solutions to basic and practical problems facing contemporary biology and biomedical sciences have been suggested, including pharmacotherapeutics and personalized medicine.

Biology Genetics Cell biology Science theoretical biology drug discovery Physics ePub

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