"Update on Amyotrophic Lateral Sclerosis" ed. by Humberto Foyaca Sibat and Lurdes de Fatima Ibanez Valdes

This book covers updated information on Amyotrophic Lateral Sclerosis (ALS) written by international researchers.

The book is comprised of 13 chapters from some of the world's top central nervous system researchers and neurologists to provide a timely review of the most recent developments in ALS, covering historic aspects, experimental animal models, genetics, pathogenesis, clinical aspects and imagenology among others.
Contributors from Belgium, France, Japan, India, Italy, Mexico, Russia, South Africa, and Switzerland have collaborated enthusiastically and efficiently, dedicating their time to create this reader-friendly yet comprehensive work which includes many explanatory figures, tables and photos to enhance legibility and make the book clinically useful. This book will play remarkable role for a new vision and mission.


Contents
Preface
1 Introductory Chapter: Introduction to Update in Amyotrophic Lateral Sclerosis and Review of this Condition in Sportsmen
2 PET Imaging in ALS
3 Motor Cortex Hyperexcitability, Neuroplasticity, and Degeneration in Amyotrophic Lateral Sclerosis
4 SOD1, from Bench to Bed: New Role for the Oldest Protein Implicated in ALS
5 Role of Cysteine Residue of Mutant Cu, Zn‐Superoxide Dismutase (SOD1) in the Pathogenesis of Amyotrophic Lateral Sclerosis (ALS)
by Seiichi Nagano and Toshiyuki Araki
6 Influence of Repeats in the Protein Chain on its Aggregation Capacity for ALS-Associated Proteins
7 MicroRNAs in Amyotrophic Lateral Sclerosis
8 Tiny microRNAs Fine-Tune Amyotrophic Lateral Sclerosis Regulation
9 Selective Vulnerability of Neuronal Subtypes in ALS: A Fertile Ground for the Identification of Therapeutic Targets
10 Neuronal Intermediate Filaments in Amyotrophic Lateral Sclerosis
11 Trophic Factors in the Therapeutic Challenge Against ALS: Current Research Directions
12 Molecular Taxonomy: Use of Transcriptional Profiles to Identify Different ALS Subtypes
13 Amyotrophic Lateral Sclerosis: Role of the Canonical Wnt/Beta- Catenin Pathway and PPAR Gamma