"Synthetic Genomics: From BioBricks to Synthetic Genomes" ed. by Miguel Fernández-Niño, Luis H. Reyes
"Synthetic Genomics: From BioBricks to Synthetic Genomes" ed. by Miguel Fernández-Niño, Luis H. Reyes
ITexLi | 2022 | ISBN: 1839696397 9781839696398 1839696389 9781839696381 1839696400 9781839696404 | 86 pages | PDF | 7 MB
ITexLi | 2022 | ISBN: 1839696397 9781839696398 1839696389 9781839696381 1839696400 9781839696404 | 86 pages | PDF | 7 MB
This book summarizes the current state of Synthetic Genomics, providing relevant examples in this emerging field.
The current advances in sequencing, data mining, DNA synthesis, cloning, in silico modeling, and genome editing have opened a new field of research known as Synthetic Genomics. The main goal of this emerging area is to engineer entire synthetic genomes from scratch using pre-designed building blocks obtained by chemical synthesis and rational design. This has opened the possibility to further improve our understanding of genome fundamentals by considering the effect of the whole biological system on biological function. Moreover, the construction of non-natural biological systems has allowed us to explore novel biological functions so far not discovered in nature.
Contents
1. From BioBricks to Synthetic Genomes
2. Multi-Omics Data Mining: A Novel Tool for BioBrick Design
3. Applications of CRISPR/Cas Technology to Research the Synthetic Genomics of Yeast
4. CRISPR-Cas9: Role in Processing of Modular Metabolic Engineered Bio-Based Products
5. Synthetic Gene Circuits for Antimicrobial Resistance and Cancer Research
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