"The Role of Matrix Metalloproteinase in Human Body Pathologies" ed. by Francesco Travascio

Matrix metalloproteinases (MMPs) are a family of proteolytic zinc-containing enzymes involved in physiological as well as in pathological processes in the human organism. MMPs play a key role in the remodeling of the extracellular matrix. Such a process may occur because of tissue homeostasis, morphogenesis, and tissue repair.

However, remodeling could also be a part of many pathological states such as arthritis, cardiovascular diseases, neurodegenerative diseases, or impaired development in congenital anomalies. This book overviews the role of MMPs in different pathologies affecting the human body.

Contents
1  Overview of MMP Biology and Gene Associations in Human Diseases
2  Heart Remodelation: Role of MMPs
3  Matrix Metalloproteinases MMP-3 and MMP-9 as Predictors of In-Stent Restenosis
4  Influence of Matrix Metalloproteinases MMP-2, -3 and on Age- Related Macular Degeneration Development
5  Retinal Ischemia: MMP-9; Its Relation to Resveratrol, Baicalein, S-allyl L-cysteine and Chi Ju Di Huang Wan
6  Skin Ageing and Cancer
7  Matrix Metalloproteinases in Melanoma with and without Regression
8  Biological Activity and Implications of the Metalloproteinases in Diabetic Foot Ulcers