"Receptors P1 and P2 as Targets for Drug Therapy in Humans" ed. by Robson Faria
"Receptors P1 and P2 as Targets for Drug Therapy in Humans" ed. by Robson Faria
ITExLi | 2020 | ISBN: 1789845351 9781789845358 1789845343 9781789845341 1838800786 9781838800789 | 91 pages | PDF | 7 MB
ITExLi | 2020 | ISBN: 1789845351 9781789845358 1789845343 9781789845341 1838800786 9781838800789 | 91 pages | PDF | 7 MB
This book aims to provide a brief update on the functions of purinergic receptors in various systems, in addition to the signaling pathway activated to mediate these functions. The book discusses some of the main bioinformatics tools currently used to improve or discover new prototypes capable of selectively acting on these receptors with estimated parameters of satisfactory solubility and toxicity for possible commercial implementation.
We address the influence of hypoxia by modulating the activity of these receptors under physiological and pathophysiological conditions. Additionally, we describe the mechanisms of induction of pain and inflammation in different systems.
Contents
1.Introductory Chapter: Receptors P1 and P2 as Targets for Drug Therapy in Humans
2.Functions of Purinergic Receptors
3.Purinergic Signaling and Dental Orofacial Pain
4.The Role of Purinergic Signaling in the Pathophysiology of Perinatal Hypoxic-Ischemic Encephalopathy
5.A Brief View of Molecular Modeling Approaches to P2 Receptors
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