"Protein Kinases" ed. by Gabriela Da Silva Xavier

This book is a collaborative effort, with contribution from experts in their respective fields, reflecting the spirit of collaboration - across disciplines and borders - that exists in modern science. Authors review the existing literature and, on occasions, provide novel data on the function of protein kinases in various systems.

Proteins are the work horses of the cell. As regulators of protein function, protein kinases are involved in the control of cellular functions via intricate signalling pathways, allowing for fine tuning of physiological functions.

Contents
Preface
1 The Target of Rapamycin: Structure and Functions
2 SNF1/AMP-Activated Protein Kinases: Genes, Expression and Biological Role
3 Alternating Phosphorylation with O-GlcNAc Modification: Another Way to Control Protein Function
4 Technologies for the Use of Protein Kinases into Medical Applications
5 Role of Kinases and Phosphatases in Host-Pathogen Interactions
6 Pathogen Strategies to Evade Innate Immune Response: A Signaling Point of View
7 Phosphorylation-Regulated Cell Surface Expression of Membrane Proteins
8 Regulation of Retrotransposition of Long Interspersed Element-1 by Mitogen-Activated Protein Kinases
9 Connexins as Substrates for Protein Kinases and Phosphoprotein Phosphatases
10 Protein Phosphatases Drive Mitotic Exit
11 Regulations and Functions of ICK/MAK/MOK - A Novel MAPK-Related Kinase Family Linked to Human Diseases
12 Protein Kinases and Protein Phosphatases as Participants in Signal Transduction of Erythrocytes
13 Role of Protein Kinase Network in Excitation-Contraction Coupling in Smooth Muscle Cell
14 Regulation of Na+/H+ Exchanger Isoform 3 by Protein Kinase Ain the Renal Proximal Tubule
15 cGMP-Dependent Protein Kinase in the Regulation of Cardiovascular Functions
16 The Crucial Role of c-Src Tyrosine Kinase in Bone Metabolism
17 The ERK МАРК Pathway in Bone and Cartilage Formation
18 Protein Kinases and Pancreatic Islet Function
19 Raf Serine/Threonine Protein Kinases: Immunohistochemical Localization in the Mammalian Nervous System
20 Protein Kinases in Spinal Plasticity: A Role for Metabotropic Glutamate Receptors
21 Protein Kinases and Pain