"Protein Interactions" Eed. by Jianfeng Cai and Rongsheng E. Wang

The objective of this book is to highlight some of the latest approaches in the study of protein interactions, including modulation of protein interactions, development of analytical techniques, etc. Collectively they demonstrate the importance and the possibility for the further investigation and modulation of protein interactions as technology is evolving.

Protein interactions, which include interactions between proteins and other biomolecules, are essential to all aspects of biological processes, such as cell growth, differentiation, and apoptosis. Therefore, investigation and modulation of protein interactions are of significance as it not only reveals the mechanism governing cellular activity, but also leads to potential agents for the treatment of various diseases.

Contents
Preface
Part 1 Examples of Protein Interactions
1 MOZ-TIF2 Fusion Protein Binds to Histone Chaperon Proteins CAF-1Aand ASF1B Through Its MOZ Portion
2 Autophagy-Mediated Defense Response of Mouse Mesenchymal Stromal Cells (MSCs)to Challenge with Escherichia coli
3 The Use of Reductive Methylation of Lysine Residues to Study Protein-Protein Interactions in High Molecular Weight Complexes by Solution NMR
4 Regulation of Protein-Protein Interactions by the SUMO and Ubiquitin Pathways
5 Functional Protein Interactions in Steroid Receptor-Chaperone Complexes
6 The TPR Motif as a Protein Interaction Module - A Discussion of Structure and Function
7 The Two DUF642 At5g11420 and At4g32460-Encoded Proteins Interact In Vitro with the AtPME3 Catalytic Domain
8 Protein-Protein Interactions and Disease
9 AApeptides as a New Class of Peptidomimetics to Regulate Protein-Protein Interactions
10 Protein Interactions in S-RNase-Based Gametophytic Self-Incompatibility
11 Direct Visualization of Single-Molecule DNA-Binding Proteins Along DNAto Understand DNA-Protein Interactions
12 Defining the Cellular Interactome of Disease-Linked Proteins in Neurodegeneration
13 Biochemical, Structural and Pathophysiological Aspects of Prorenin and (Pro)renin Receptor
14 Cholesterol-Binding Peptides and Phagocytosis
Part 2 Studying Protein Interactions
15 One-by-One Sample Preparation Method for Protein Network Analysis
16 Live In-Cell Visualization of Proteins Using Super Resolution Imaging
17 Approaches to Analyze Protein-Protein Interactions of Membrane Proteins
18 Relating Protein Structure and Function Through a Bijection and Its Implications on Protein Structure Prediction
19 Protein-DNA Interactions Studies with Single Tethered Molecule Techniques
20 Characterization of Protein-Protein Interactions via Static and Dynamic Light Scattering
21 Site-Directed Spin Labeling and Electron Paramagnetic Resonance (EPR) Spectroscopy: A Versatile Tool to Study Protein-Protein Interactions
22 Modification. Development, Application and Prospects of Tandem Affinity Purification Method