"Pluripotent Stem Cells: From the Bench to the Clinic" ed. by Minoru Tomizawa

In this book, embryonic stem cells, induced pluripotent stem cells, and mesenchymal stem cells are discussed. Readers are expected to gain useful information from expert contributors.

Pluripotent stem cells have distinct characteristics: self-renewal and the potential to differentiate into various somatic cells. In recent years, substantial advances have been made from basic science to clinical applications. The vast amount knowledge available makes obtaining concise yet sufficient information difficult, hence the purpose of this book.
The book is divided into five sections: pluripotency, culture methods, toxicology, disease models, and regenerative medicine. The topics covered range from new concepts to current technologies.

Contents
Preface
1 Introductory chapter: Pluripotent stem cells
2 Embryonic Stem Cells: Keeping Track of the Pluripotent Status
3 States of Pluripotency: Naïve and Primed Pluripotent Stem Cells
4 Pluripotent Stem Cells and Their Dynamic Niche
5 Rejuvenation on the Road to Pluripotency
6 Genomic Instability of Pluripotent Stem Cells: Origin and Consequences
7 Moving toward Xeno-free Culture of Human Pluripotent Stem Cells
8 Affordable Clean Air Facility for (Stem) Cell Therapy in an Academic Setting
9 Induced Pluripotent Stem Cells for Clinical Use
10 Pluripotent Stem Cells in Toxicity Testing: An Omics Approach
11 Nontargeted Metabolite Profiling of Induced Pluripotent Stem Cells (iPSCs) Derived Neural Cells: Insights Into Mechanisms of Brain Diseases
12 Modeling Hypertrophic Cardiomyopathy with Human Induced Pluripotent Stem Cells
13 Stem Cells for Modeling Human Disease
14 Modelling Neurodegenerative Diseases Using Human Pluripotent Stem Cells
15 From Human Pluripotent Stem Cells to Peripheral Neurons
16 Temporal Dynamics of Spontaneous Ca2+ Transients, ERBB4, vGLUT1, GAD1, Connexin, and Pannexin Genes in Early Stages of Human Stem Cell Neurodifferentiation
17 Pluripotent Stem Cells: Differentiation Potential and Therapeutic Efficacy for Cartilage Repair
by Wei Seong Toh
18 Cartilage Regeneration Using Pluripotent Stem Cell‐Derived Chondroprogenitors: Promise and Challenges
19 Retinoic Acid Receptor Signaling in the Differentiation of Pluripotent Stem Cells into Skeletal Muscle Lineage
20 Generating Self-Organizing Stomach Tissue from Mouse Embryonic Stem Cells
21 Human Embryonic Stem Cells and Induced Pluripotent Stem Cells: The Promising Tools for Insulin-Producing Cell Generation
22 Stem Cell-Derived Regulatory T Cells for Therapeutic Use
23 Mesenchymal Stem Cells: Biological Characteristics and Potential Clinical Applications for Haematopoietic Stem Cell Transplantation