"Pheochromocytoma, Paraganglioma and Neuroblastoma" ed. by Pasquale Cianci, Enrico Restini, Amit Agrawal

This book discusses epidemiology, genetics, and treatment of Pheochromocytoma, paraganglioma and neuroblastoma malignancies.

Pheochromocytoma, paraganglioma and neuroblastoma are the most common neural crest-derived tumors in adults and children, respectively. These neoplasms are associated with significant morbidity and mortality. Some international studies currently underway are researching and evaluating the presence of any similarities and differences between these tumors. Hopefully, future results will reveal several potential novel genes and pathways that might have major roles in the pathogenesis and progression of these neoplasms.

Contents
1. Introductory Chapter: Neural Crest Cell-Derived Tumors. An Introduction on Pheocromocytoma, Paraganglyoma and Neuroblastoma
2. Pheochromocytomas and Paragangliomas: Genotype-Phenotype Correlations
3. Metastatic Paragangliomas and Pheochromocytomas: An Epigenetic View
4. Surgical Approach in Pheochromocytoma
5. Primary Central Nervous System Neuroblastoma: An Enigmatic Entity
6. The Scaffold Protein p140Cap as a Molecular Hub for Limiting Cancer Progression: A New Paradigm in Neuroblastoma
7. Targeting MYC and HDAC8 with a Combination of siRNAs Inhibits Neuroblastoma Cells Proliferation In Vitro and In Vivo Xenograft Tumor Growth


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