"New Insights into Inflammatory Bowel Disease" ed. by Samuel Huber

This book aims to summarize basic aspects of these complex interactions between barrier function, microbiome, and the immune system. Of note, there is currently no cure for IBD. However, several therapies have evolved in the last years, which are overall able to-at least temporarily-suppress IBD. These therapies and the underlying mechanism are discussed.

The incidence of chronic inflammatory and autoimmune diseases is steadily increasing. Inflammatory bowel disease (IBD) is one example of a chronic inflammatory disease, which primarily affects the intestine but may also affect extraintestinal organs. The exact pathogenesis of IBD is currently unknown.
However, it is clear that the pathogenesis is complex, involving barrier defects, changes in the intestinal microbiome, and chronic immune activation.


Contents
Preface
1 Inflammatory Bowel Disease: Epidemiology
2 Inflammatory Bowel Disease: The Association of Inflammatory Cytokine Gene Polymorphisms
3 Genetic and Serological Markers in Identifying Unclassified Colitis
4 Cytokines in Inflamed Mucosa of IBD Patients
5 Interleukin 23 in IBD Pathogenesis
6 Cytokines and Nitric Oxide in Immunopathogenesis of IBD and Potential Therapeutic Approaches
7 MicroRNA in Inflammatory Bowel Disease
8 Intestinal Fibroblast/Myofibroblast TRP Channels in Inflammatory Bowel Disease
9 Microbial Neuro-Immune Interactions and the Pathophysiology of IBD
10 Oral Tacrolimus in Patients with Ulcerative Colitis
11 Probiotics and Crohn’s Disease
12 Autologous and Allogeneic Stem Cell Transplantation for Treatment of Crohn’s Fistulae

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Inflammatory Diseases - Modern Perspective
Inflammatory Bowel Disease
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