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    Marfan Syndrome: A Primer for Clinicians and Scientists

    Posted By: yousufhunk
    Marfan Syndrome: A Primer for Clinicians and Scientists

    Marfan Syndrome: A Primer for Clinicians and Scientists
    Springer | November 2, 2004 | ISBN-10: 030648238X | 232 pages | PDF | 3.25 MB

    Marfan Syndrome is a hereditary disorder of connective tissue which primarily affects the cardiovascular, skeletal, and ocular systems. Remarkable progress in the field has been made in both clinical and basic-science research since the discovery of the gene for fibrillin-1 (FBN1) in 1991, mutations in which cause the Marfan syndrome. Marfan Syndrome: A Primer for Clinicians and Scientists presents a comprehensive overview of clinical aspects of Marfan syndrome, FBN1 mutation analysis, the biology of fibrillin and fibrillin-containing microfibrils, and the molecular pathogenesis of the Marfan syndrome. The authors are prominent and active researchers in clinical and basic-science research on Marfan syndrome and fibrillin.