"Major Depressive Disorder: Cognitive and Neurobiological Mechanisms" ed. by Yong-Ku Kim

The aim of this book is to describe current knowledge of Major depressive disorder (MDD) from the point of view of neurobiology, molecular genetics and cognition. The authors address a deep understanding of cognitive and neurobiological mechanisms involved in MDD.

Major depressive disorder (MDD) is a complex and heterogeneous disorder, phenotypically and biologically. MDD may be caused by complex interaction between genes and environment in susceptible individuals. Thus, a combination of certain genetic polymorphism, environmental stress, and personal susceptibility ultimately may induce MDD. Gene-environment interactions in the pathophysiology of MDD lead to advancement in personalized medicine by means of genotyping for inter-individual variability in drug action and metabolism. Gene-environment interactions may explain why some subjects become depressed while others remain unaffected.

Contents
Preface
1 Different Mechanisms Between Melancholic and Atypical Depression
2 Neurotrophic Factors and Major Depressive Disorder
3 The Molecular and Quantum Approach to Psychopathology and Consciousness — From Theory to Experimental Practice
4 The Effects of Psychotherapy on Brain Function — Major Depressive Disorder
5 The Neural Mechanism of Negative Cognitive Bias in Maior Depression — Theoretical and Empirical Issues
6 Impaired Mental Processing Speed With Moderate to Severe Symptoms of Depression