"Lupus: New Advances and Challenges" ed. by Sophia Lionaki
"Lupus: New Advances and Challenges" ed. by Sophia Lionaki
ITExLi | 2020 | ISBN: 838801707 9781838801700 1838801693 9781838801694 1838801847 9781838801847 | 118 pages | PDF | 5 MB
ITExLi | 2020 | ISBN: 838801707 9781838801700 1838801693 9781838801694 1838801847 9781838801847 | 118 pages | PDF | 5 MB
This book covers important aspects of the disease, including epidemiology, pathophysiology, and neuropsychiatric manifestations, including basic science and clinical features and management.
Systemic lupus erythematosus, the prototype of an autoimmune disorder, may affect several organs and may run a chronic course between relapse and remission.
In affected patients, the fundamental problem of fertility is reassessed including the risk of the disease, the possibility of fetal loss, the safety of drugs during pregnancy, and the current diagnostic and suggested therapeutic strategies of reproductive medicine. Finally, the issue of pathogenesis is revisited with a thorough description of animal models in relation to physiology and potential novel therapies.
Contents
1.Introductory Chapter: Recent Advances in Systemic Lupus Erythematosus
2.Epidemiology of Systemic Lupus Erythematosus
3.A Spontaneous Mouse Model of Lupus: Physiology and Therapy
4.Reproductive Environment in Patients with SLE
5.Lupus Pregnancy: Risk Factors and Management
6.Neuropsychiatric SLE: From Immune Mechanisms to Clinical Management
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