"Immune Response Activation and Immunomodulation" ed. by Rajeev Tyagi, Prakash Singh Bisen

This volume has been written to address the perceived needs of both medical school and undergraduate curricula and to take advantage of new understandings in immunology. This book gives an insight into the role of cytokines in activating immune response during pathogenic invasion.

Authors have tried to achieve several goals and present the most important principles governing the function of the immune system. Our fundamental objective has been to synthesize the key concepts from the vast amount of experimental data that have emerged in the rapidly advancing field of immunology.
The choice of what is most important is based on what is most clearly established by experimentation, what our students find puzzling, and what explains the wonderful efficiency and economy of the immune system. Inevitably, however, such a choice will have an element of bias, and our bias is toward emphasizing the cellular interactions in immune response by limiting the description of many of the underlying biochemical and molecular mechanisms to the essential facts.
Immunomodulation, aryl hydrocarbons, the role of the protein defensin and nucleated cells in provoking immune response, Bcl protein/gene-based apoptotic pathways, and plant-derived phytochemical-mediated immune response are all central themes of this book.


Contents
1. Introductory Chapter: Immunity and Immunomodulation
2. Cytokine Profiling Plays a Crucial Role in Activating Immune System to Clear Infectious Pathogens
3. Nucleated Red Blood Cells Contribute to the Host Immune Response Against Pathogens
4. Multifunctional Activity of the β-Defensin-2 during Respiratory Infections
5. Immune Cell Activation: Stimulation, Costimulation, and Regulation of Cellular Activation
6. Mesenchymal Stem Cells Modulate the Immune System in Developing Therapeutic Interventions
7. Current State of the Art in DNA Vaccine Delivery and Molecular Adjuvants: Bcl-xL Anti-Apoptotic Protein as a Molecular Adjuvant
8. Role of Aryl Hydrocarbon-Ligands in the Regulation of Autoimmunity