"Glucose Tolerance" ed. by Sureka Chackrewarthy

This book summarises the current state of knowledge on the pathophysiology underlying the progression from normal glucose tolerance to type 2 diabetes and therapeutic advances in the improvement of glycaemic control in prediabetic and diabetic states.

The progression from normal glucose tolerance (NGT) to type 2 diabetes involves intermediate stages of impaired fasting glucose (IFG) and impaired glucose tolerance (IGT), also known as prediabetes. The pathophysiology underlying the development of these glucose metabolic alterations is multifactorial, leading to an alteration in the balance between insulin sensitivity and insulin secretion.
Our knowledge of the molecular basis of the signaling pathways mediating the various physiologic effects of insulin is steadily advancing. New substrates and signaling molecules have been identified and potential mechanisms involved in the pathophysiology of type 2 diabetes have been revealed.

Contents
Preface
Section 1 Impaired Glucose Tolerance: Diagnosis, Prognosis and Treatment
1 The Glucose Tolerance Test as a Laboratory Tool with Clinical Implications
2 Can We Prevent or Delay Type 2 Diabetes?
Section 2 Insights into Potential Mechanisms of Insulin Resistance
3 Impaired Glucose Tolerance. Obesity and Inflammatory Mediators
4 Sex Differences in Obesity-Related Glucose Intolerance and Insulin Resistance
5 Age is an Important Risk Factor for Type 2 Diabetes Mellitus and Cardiovascular Diseases
6 Glucose Tolerance and Elders - Lessons We Have Learned and Challenges for the Future
7 The Relationship Between Chronic Alcohol Use and Type 2 Diabetes Mellitus: New Insights into Mechanisms of Appetite-Regulating Peptides
Section 3 Dietary Constituents and Insulin Resistance
8 Importance of Dietary Fatty Acid Profile and Experimental Conditions in the Obese Insulin- Resistant Rodent Model of Metabolic Syndrome
9 Intestinal Disaccharidase Activity and Uptake of Glucose from Sucrose
Section 4 Novel Therapeutic Targets and Pharmacologic Compounds with Antidiabetic Potential
10 Glucose Tolerance Factor - Insulin Mimetic and Potentiating Agent - A Source for a Novel Anti Diabetic Medication
11 Medicinal Plants and Natural Compounds from the Genus Morus (Moraceae) with Hypoglycemic Activity: A Review
12 Hypoglycaemic and Hypolipidaemic Effects of an Ethylacetate Fraction ofArtocarpus heterophyllus Leaves
13 Non-Obese Type 2 Diabetes Animals Models