"Extracellular Matrix: Developments and Therapeutics" ed. by Rama Sashank Madhurapantula, Joseph Orgel, Zvi Loewy

This book reports research and new developments in the field of collagen structure, function, and biomechanics and discusses the relevance of hyaluronic acid and its therapeutic uses. It gives readers a glimpse of what is current in this area and we hope it piques their interest in learning more about ECM biology.

Extracellular matrix (ECM) is an extensive molecule network composed of three major components: protein, glycosaminoglycan, and glycoconjugate. ECM components, as well as cell adhesion receptors, interact with each other forming a complex network into which cells reside in all tissues and organs. Understanding ECM structure and function is important for developing biomedical applications that are as close to ‘native’ as possible. The book is written by pioneering scientists from all over the world.

Contents
1. The Cellular Stress Response Interactome and Extracellular Matrix Cross-Talk during Fibrosis: A Stressed Extra-Matrix Affair
2. Extracellular Matrix in Cardiac Tissue Mechanics and Physiology: Role of Collagen Accumulation
3. The Extracellular Matrix of the Human and Whale Cornea and Sclera: Implications in Glaucoma and Other Pathologies
4. The Evolutionary Origin of Elastin: Is Fibrillin the Lost Ancestor?
5. The Interplay of ECM-Based Graft Materials and Mechanisms of Tissue Remodeling
6. Hyaluronic Acid Fillers: Where We Have Been and Where We Are Going
7. Hyaluronic Acid Derivatives for Targeted Cancer Therapy
8. Plant Natural Products: A Promising Source of Hyaluronidase Enzyme Inhibitors


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