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"Drug Repurposing: Hypothesis, Molecular Aspects and Therapeutic Applications" ed. by Farid A. Badria

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"Drug Repurposing: Hypothesis, Molecular Aspects and Therapeutic Applications" ed. by Farid A. Badria

"Drug Repurposing: Hypothesis, Molecular Aspects and Therapeutic Applications" ed. by Farid A. Badria
ITexLi | 2020 | ISBN: 1839685212 9781839685217 1839685204 9781839685200 1839685220 9781839685224 | 211 pages | PDF |9 MB

This book focuses on the hypothesis, risk/benefits, and economic impacts of drug repurposing on drug discovery in dermatology, infectious diseases, neurological disorders, cancer, and orphan diseases. It brings together up-to-date research to provide readers with an informative, illustrative, and easy-to-read book useful for students, clinicians, and the pharmaceutical industry.

Drug repurposing or drug repositioning is a new approach to presenting new indications for common commercial and clinically approved existing drugs. For example, chloroquine, an old antimalarial drug, showed promising results for treating COVID-19, interfering with MDR in several types of cancer, and chemosensitizing human leukemic cells.

Contents
1. Drug Repurposing (DR): An Emerging Approach in Drug Discovery
2. Risk-Benefit Events Associated with the Use of Aspirin for Primary Prevention of Cardiovascular Disorders
3. Drug Repurposing in Dermatology: Molecular Biology and Omics Approach
4. Drug Repurposing and Orphan Disease Therapeutics
5. Drug Repurposing in Neurological Diseases: Opportunities and Challenges
6. Drugs Repurposing for Multi-Drug Resistant Bacterial Infections
7. Drug Repurposing in Oncotherapeutics
8. Drug Repositioning for the Treatment of Glioma: Current State and Future Perspective
9. Repurposing Infectious Pathogen Vaccines in Cancer Immunotherapy
10. Salicylic Acid Sans Aspirin in Animals and Man
11. Repurposing Fumaric Acid Esters to Treat Conditions of Oxidative Stress and Inflammation: A Promising Emerging Approach with Broad Potential

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