"Colorectal Cancer: From Pathogenesis to Treatment" ed. by Luis Rodrigo

This volume is dedicated to colorectal cancer (CRC). A better understanding of the biology of the tumor, along with high efficiency of diagnostic and therapeutic methods, as well as the spread of screening programs, will improve the survival of the CRC patients in the near future.

Colorectal cancer (CRC) is a major health problem because it represents around 10% of all cancers and achieves a worldwide estimate of 1.4 million newly diagnosed cases annually, resulting in approximately 700,000 deaths.
Approximately 19-31% of patients present liver metastases. At diagnosis, a further 23-38% will develop extra-hepatic disease. Over the past decade, the widespread use of modern chemotherapeutic and biological agents, combined with laparoscopic surgical techniques, has improved the prognosis of metastatic CRC.


Contents
Preface
1 Molecular Mechanisms Involved in the Acquisition of Resistance to Treatment of Colon Cancer Cells
2 Circadian Regulation of Colon Cancer Stem Cells: Implications for Therapy
3 Modulation of Apoptosis in Colon Cancer Cells by Bioactive Compounds
4 BRAF Mutation in Colorectal Cancer
5 Colorectal Cancer Prevention and Risk Counseling
6 Imaging of Colonic and Rectal Cancer
7 Endoscopic Submucosal Dissection for Early Colon Cancer
8 Colorectal Cancer and Inflammatory Bowel Disease
9 Laparoscopy in the Management of Colon Cancer
10 Current Immunotherapeutic Treatments in Colon Cancer
11 The Management of the Primary Tumor in Patients with Metastatic Colorectal Cancer
12 Simultaneous Surgery for Synchronous Colorectal Liver Metastases
13 Adjuvant Treatment in Colon Cancer
14 Robot-Assisted Colonic Resections for Cancer
15 Immunotherapy in Colorectal Cancer
16 New Chemotherapeutic Agents: Monoterpenes and Fatty Acid Synthase Inhibitors
17 Anti-Epidermal Growth Factor Receptor (EGFR) Treatment in Patients with Metastatic Colorectal Cancer
18 Studies of Malaysian Plants in Prevention and Treatment of Colorectal Cancer
19 Adjuvant Systemic Therapy in Stage II and III Colon Cancer