"Biological Therapy for Inflammatory Bowel Disease" ed. by Raquel Franco Leal, Tristan Torriani

The aim of this book is to provide an overview of such drugs and the latest developments in inflammatory bowel disease (IBD) immunopathology. Authors discuss the main indications, efficacy, and possible side effects of the different types of drugs available today for IBD treatment.

The treatment of inflammatory bowel disease (IBD) has posed a major challenge since its appearance. Biomedical researchers, physicians, gastroenterologists, and surgeons have struggled to improve the quality of life of their patients and have sought, above all else, to keep the disease under remission for as long as possible. Blockers for tumoral necrosis factor alpha (TNF-α) were the first biological drugs to be discovered and for this reason they played a crucial role in the subsequent evolution of IBD treatment.


Contents
1.Mucosal Immunology in the Inflammatory Bowel Diseases
2.The Role of TNF in the Pathogenesis of Inflammatory Bowel Disease
3.Traditional Drugs: Mechanisms of Immunosuppressor and Corticosteroid Therapies for Inflammatory Bowel Diseases
4.Inhibitors of Tumoral Necrosis Factor Alpha in Inflammatory Bowel Disease
5.Biological Therapy in the Prevention of Complications of Crohn
6.Biological Therapy for Inflammatory Bowel Diseases: Screening Prior to Initiating and How to Proceed When Surgery Is Necessary
7.Anti-Integrins, Anti-Interleukin 12/23p40, and JAK Inhibitors for the Inflammatory Bowel Disease Treatment