"Biochemistry" by Donald Voet, Judith G. Voet

This textbook is a distillation of oauthor's experiences in teaching undergraduate and graduate students and is intended to provide such students with a thorough grounding in biochemistry.


The text is organized into five parts:
I. Introduction and Background: An introductory chapter followed by chapters that review the properties of aqueous solutions and the elements of thermodynamics.
II. Biomolecules: A description of the structures and functions of proteins, nucleic acids, carbohydrates, and lipids.
III. Mechanisms of Enzyme Action: An introduction to the properties, reaction kinetics, and catalytic mechanisms of enzymes.
IV. Metabolism: A discussion of how living things synthesize and degrade carbohydrates, lipids, amino acids, and nucleotides with emphasis on energy generation and consumption.
V. Expression and Transmission of Genetic Information: An expansion of the discussion of nucleic acid structure that is given in Part II followed by an exposition of both prokaryotic and eukaryotic molecular biology.

This organization permits us to cover the major areas of biochemistry in a logical and coherent fashion.

TOC
PART I INTRODUCTION AND BACKGROUND
1 Life
2 Aqueous Solutions
3 Thermodynamic Principles: A Review
PART II BIOMOLECULES
4 Amino Acids
5 Nucleic Acids, Gene Expression, and Recombinant DNA Technology
6 Techniques of Protein and Nucleic Acid Purifications
7 Covalent Structures of Proteins and Nucleic Acids
8 Three-Dimensional Structures of Proteins
9 Protein Folding, Dynamics, and Structural Evolution
10 Hemoglobin: Protein Function in Microcosm
11 Sugars and Polysaccharides
12 Lipids and Membranes
PART III MECHANISMS OF ENZYME ACTION
13 Introduction to Enzymes
14 Rates of Enzymatic Reactions
15 Enzymatic Catalysis
PART IV METABOLISM
16 Introduction to Metabolism
17 Glycolysis
18 Glycogen Metabolism
19 Signal Transduction
20 Transport through Membranes
21 Citric Acid Cycle
22 Electron Transport and Oxidative Phosphorylation
23 Other Pathways of Carbohydrate Metabolism
24 Photosynthesis
25 Lipid Metabolism
26 Amino Acid Metabolism
27 Energy Metabolism: Integration and Organ Specialization
28 Nucleotide Metabolism
PART V EXPRESSION AND TRANSMISSION OF GENETIC INFORMATION
29 Nucleic Acid Structures
30 DNA Replication, Repair, and Recombination
31 Transcription
32 Translation
33 Viruses: Paradigms for Cellular Function
34 Eukaryotic Gene Expression
35 Molecular Physiology