Autophagy at the Cell, Tissue and Organismal Level
Autophagy at the Cell, Tissue and Organismal Level
Springer | Cell Biology | May 25, 2016 | ISBN-10: 3319331434 | 116 pages | pdf | 2.17 mb
Springer | Cell Biology | May 25, 2016 | ISBN-10: 3319331434 | 116 pages | pdf | 2.17 mb
Authors: Karanasios, Eleftherios, Ktistakis, Nicholas T.
Covers autophagy from the basic mechanisms to its effects at the cell, tissue and organism level
Includes an extensive list of antibodies for the study of autophagy
Written by experts in the field
This book provides an expert summary of autophagy, a relatively new but rapidly expanding field of biomedical science with important implications in health and disease. After a historical review ranging up to the identification of autophagy genes in mammals, the authors discuss the signaling pathways that regulate autophagy, the mechanism of autophagosome formation and the physiological roles of autophagy in development, ageing, neurodegeneration, immune function and cell differentiation. A comprehensive list of useful antibodies for studying autophagy compiled as a community effort is included at the end. The book is intended for newcomers to the field, as well as more experienced researchers looking for a condensed but comprehensive introduction to the physiological function and regulation of the autophagic pathway in mammalian organisms.
Number of Illustrations and Tables
3 b/w illustrations, 12 illustrations in colour
Topics
Cell Biology
Immunology
Animal Biochemistry
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