Antibody Engineering: Foundations & Therapeutic Applications

Master antibody basics, hybridoma technology, display systems, CAR-T, bispecifics, and ADCs in cancer immunotherapy

What you'll learn
- Grasp the entire antibody‑engineering workflow – from discovery and hybridoma tech to CAR‑T, bi-specifics, and ADCs.
- Decode antibody structure–function basics and see how molecular tweaks boost affinity, stability, and safety.
- Compare cutting‑edge platforms like phage/yeast display, transgenic animals, and in‑silico design for rapid hit discovery.
- Apply real‑world case studies (Blinatumomab, CAR‑T therapies) to plan R&D or clinical strategies.

Requirements
- High‑school level biology or first‑year university life‑science knowledge.
- Curiosity about biologics, immunology, or drug development.
- No lab access required – all concepts are explained visually.

Description
Unlock the world of antibody engineering in this foundational course designed for students, researchers, and life science professionals. Whether you're new to biotechnology or looking to solidify your understanding of antibody-based therapeutics, this course provides a structured, beginner-friendly introduction to one of the most powerful tools in modern medicine.

You will begin with the discovery and structural properties of antibodies and quickly move into revolutionary technologies like hybridoma systems, antibody display platforms (e.g., phage, mammalian and yeast display), and humanized antibody production using transgenic animals. I will explore how these engineered antibodies are reshaping therapeutic strategies in cancer, autoimmune disease, and infectious disease.

Dive deeper into cutting-edge antibody modalities, including bispecific antibodies, antibody-drug conjugates (ADCs), and CAR-T cell therapy. These tools are transforming clinical outcomes for patients with previously untreatable diseases.

By the end, you will be equipped with the foundational knowledge to understand antibody therapeutics, contribute to research teams, or pursue more advanced training.

No prior experience in immunology is required—just curiosity and a passion for science and innovation.

What You will Learn:

Basics of antibody structure and function

How monoclonal antibodies are made using hybridomas

How display systems revolutionized antibody selection

The use of antibodies in diagnostics and therapy

Mechanisms of bispecific antibodies and ADCs

The role of antibodies in CAR-T cells and future applications

Who this course is for:
- Life‑science students exploring biotech careers for building a rock‑solid antibody engineering foundation for internships or MSc/PhD applications.
- Bench scientists / research associates moving into biologics for fast‑tracking your transition from small‑molecule or academic work to therapeutic antibody projects.
- Clinicians & pharmacists wanting to interpret clinical trial data, advise patients, and collaborate with R&D teams more confidently.
- Entrepreneurial founders & investors eyeing next‑gen biologics to spot technological white‑spaces and evaluate platform start‑ups with a scientific lens.
- Curious self‑learners who love immunology breakthroughs to enjoy an engaging, jargon‑free tour of the science behind today’s blockbuster biologics.
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