"Adipose Tissue: An Update" ed. by Leszek Szablewski

This book describes a series of up-to-date topics about physiological and pathological processes in adipose tissue.

Adipose tissue, a kind of connective tissue, plays different and significant roles in the human body. Its function includes protection against environmental factors, storage of lipids and triacylglycerol, and the process of thermogenesis. It is also involved in the secretion of highly active biomolecules such as steroid hormones, prostaglandins, as well as proteins called “adipokines.” On the other hand, disturbances in functions of adipose tissue may cause several pathologies such as obesity and insulin resistance. Obesity is a worldwide health problem, whereas diabetes mellitus due to insulin resistance is defined by the World Health Organization as “a progressive worldwide epidemic.” Especially dangerous is visceral accumulation of adipose tissue.

Contents
1.Introductory Chapter: Adipose Tissue
2.Role of Sirtuins in Adipose Tissue Development and Metabolism
3.Novel Aspects of Follistatin/Transforming Growth Factor-β (TGF-β) Signaling in Adipose Tissue Metabolism: Implications in Metabolic Health
4.Effect of Alcohol on Gut-Liver Axis and Adipose Tissue
5.Adipose Tissue Inflammation and Metabolic Disorders
6.Lipedema: A Painful Adipose Tissue Disorder
7.Mediators of Impaired Adipogenesis in Obesity-Associated Insulin Resistance and T2DM