Freeze-drying Technology in Pharmaceutical and Biomedical Product Development
Freeze-drying Technology in Pharmaceutical and Biomedical Product Development:
Impact, Progress and Challenges of Lyophilization
English | 2025 | ISBN: 9819502209 | 374 Pages | PDF (True) | 15 MB
Impact, Progress and Challenges of Lyophilization
English | 2025 | ISBN: 9819502209 | 374 Pages | PDF (True) | 15 MB
Freeze drying, sometimes referred to as lyophilization, is an essential method in biomedical and pharmaceutical industries that allows for extremely accurate preservation of sensitive biological components. This book highlights freeze drying operation, the different types of freeze-dryers, development of the freeze-drying cycle, and characterization of freeze-dried goods. It also explores the crucial connection between freeze drying and colloidal dispersions' stability, illuminating the complex interactions between formulation composition, processing variables, and stability of the final product. It focuses on the benefits of this method for stabilizing essential biopharmaceuticals such as probiotics, recombinant proteins and monoclonal antibodies by preventing aggregation and degradation and sustaining their therapeutic effectiveness for longer periods of time. Apart from the chemistry, operations and benefits, this book explores new possibilities for precisely and deeply describing freeze-dried products by discussing the most recent developments in analytical methods.