Tissue Engineering for Degenerative Intervertebral Discs

by Jun Zou (Author)

Low back pain is a common disorder in the clinical treatment of the Department of Orthopedics. Lumbar intervertebral disc degeneration is a main reason for the chronic pain and the process is difficult to reverse. Traditional treatment methods include conservative treatment and surgical treatment. Although the clinical symptoms caused by intervertebral disc degeneration can be alleviated to a certain extent, these treatment methods do not solve the fundamental issues and they also produce corresponding complications. The rise of tissue engineering technology and its applications in different fields have brought new ideas for the treatment of intervertebral disc degeneration. This book discusses the fundamentals as well as more recent developments in stem cell therapy and tissue engineering technology and offers an alternative for treating degeneration of intervertebral discs.


Contents:
Introduction
Progress in Tissue Engineering
Stem Cells and Regenerative Medicine Research
The Structural and Functional Characteristics of the Intervertebral Disc
Cell and Molecular Therapy in the Study of Intervertebral Disc Degeneration
The Research Status and Progress of Stem Cell Therapy in the Regeneration of Degenerated Intervertebral Discs
Seed Cells
Tissue Engineering and Cell Scaffold
Growth Factors
Bone Marrow Mesenchymal Stem Cells and Their Application in Intervertebral Disc Tissue Engineering
Silk Fibroin in the Tissue Engineering of Intervertebral Disc Annulus


Readership: Medical students and practitioners working in the orthopedic department of hospitals, or researchers interested in tissue engineering therapy