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    3. Evolution-adjusted Tumor Pathophysiology:: The Novel Language of Tumor Biology

    Evolution-adjusted Tumor Pathophysiology:: The Novel Language of Tumor Biology

    Posted By: roxul
    Date: 5 Sep 2019 10:53:23
    Evolution-adjusted Tumor Pathophysiology:: The Novel Language of Tumor Biology

    Albrecht Reichle, "Evolution-adjusted Tumor Pathophysiology:: The Novel Language of Tumor Biology"
    English | ISBN: 9400768656 | 2013 | 453 pages | EPUB, PDF | 7 MB + 12 MB

    Combined modularized therapies for metastatic cancer are pointing to central problems of communication among ‘systems participators’. A communication theory explains `social engineering`, endogenously induced or by implementing non-normative boundary conditions. Evolution-adjusted tumor pathophysiology is borne by an evolution theory, which contrasts narrative evolution histories. The tool of rationalizations constituting the tumor`s normativity (inflammation, immune response etc.) represents the non-genomic counterpart of the tumor genome and should be additionally assessed during tumor staging. Evolution-adjusted tumor pathophysiology allows implementing applied systems biology, a novel clinical and pharmaceutical technology for bioengineering tumor response and personalizing tumor therapy. Combined modularized therapy, evolution-adjusted tumor pathophysiology, and ‘universal’ biomarkers concertedly address genetically based tumor heterogeneity.
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