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    Comprehensive Biomarker Discovery and Validation for Clinical Application

    Posted By: insetes
    Comprehensive Biomarker Discovery and Validation for Clinical Application

    Comprehensive Biomarker Discovery and Validation for Clinical Application By Horvatovich, Peter; Bischoff, Rainer; Thurston, David E; Fox, David; Rotella, David
    2012 | 384 Pages | ISBN: 1849734224 | PDF | 10 MB


    Content: Introduction to biomarker discovery and validation; Clinical context of proteomics biomarker discovery and validation, authority regulations; Biomarker discovery: Patient selection; Biomarker discovery: Experimental design and biobanking; Biomarker discovery: body fluids; Biomarker discovery: tissues; Biomarker discovery: mass spectrometry based profiling platforms; Biomarker discovery: array based profiling platforms; Biomarker discovery: data preprocessing for LC-MS data; Biomarker discovery: data preprocessing for Maldi imaging, and 2D electrophoresis and protein arrays data; Biomarker discovery: statistical analysis and validation; Biomarker validation: biomarker validation methods; Functional biomarker validation; Clinical application: case studies Clinical application: summary and future technology development trends