Phosphoinositides. Chemistry, Biochemistry, and Biomedical Applications

Content: The structural and functional versatility of inositol phosphates / James J. Caffrey, Stephen T. Safrany, Xiaonian Yang, Masako Yoshida, and Stephen B. Shears -- Probing phosphoinositide polyphosphate binding to proteins / Glenn D. Prestwich, Anu Chaudhary, Jian Chen, Li Feng, Bharat Mehrotra, and Jirong Peng -- Differential recognition of phosphoinositides by actin regulating proteins and its physiological implications / Pei-Jung Lu, Da-Sheng Wang, Keng-Mean Lin, Helen L. Yin, and Ching-Shih Chen -- Studies on new ins(1,4,5)P₃ binding proteins with reference to the pH domains / Takashi Kanematsu, Hiroshi Takeuchi, and Masato Hirata -- Structure and mechanism of Ca²-independent phosphatidylinositol-specific phospholipases C / Dirk W. Heinz, Jürgen Wehland, and O. Hayes Griffith -- Characterization of the histidine residues of B. cereus Phosphatidylinositol-specific phospholipase C by NMR / Tun Liu, Margret Ryan, Frederick W. Dahlquist, and O. Hayes Griffith -- Mechanism of phosphatidylinositol-specific phospholipase C revealed by protein engineering and phosphorothioate analogs of phosphatidylinositol / Robert J. Hondal, Zhong Zhao, Alexander V. Kravchuk, Hua Liao, Suzette R. Riddle, Karol S. Bruzik, and Ming-Daw Tsai -- Structural analysis of the catalysis and membrane association of PLC-[delta]₁ / L.-O. Essen, P.D. Brownlie, O. Perisic, M. Katan, and R.L. Williams -- Sequential mechanism and allosteric activation of phosphoinositide-specific phospholipase C-[delta]₁ / Mary F. Robert, Yiqin Wu, Olga Perisic, Roger L. Williams, and Matilda Katan -- Structure-activity relationships of adenophostin A and related molecules at the 1-D-myo-inositol 1,4,5-trisphosphate receptor / Barry V.L. Potter -- Stereospecific syntheses of inositol phospholipids and their phosphorothioate analogs / Robert J. Kubiak, Xiangjun Yue, and Karol S. Bruzik -- Chemical synthesis of phosphatidylinositol phosphates and their use as biological tools / Yutaka Watanabe -- Synthesis of phosphatidyl-myo-inositol polyphosphates and derivatives / Shoichiro Ozaki, Yutaka Watanabe, Takehiro Maekawa, Yuichi Higaki, Tomio Ogasawara, and Xiang Zheng Kong -- Syntheses of 2-modified phosphatidylinositol 4, 5-bisphosphates : putative probes of intracellular signaling / R. Aneja and S.G. Aneja -- Membrane-permeant, bioactivatable derivatives of inositol polyphosphates and phosphoinositides / Carsten Schultz, Marco T. Rudolf, Hartmut H. Gillandt, and Alexis E. Traynor-Kaplan -- Synthesis of inositol-containing glycophospholipids with natural and modified structure / Alexander E. Stepanov and Vitaly I. Shvets -- Inositol phosphates : inframolecular physico-chemical studies : correlation with binding properties / G. Schlewer, P. Guédat, S. Ballereau, L. Schmitt, and B. Spiess -- 5-Deoxy-5-fluoro-1-O-phosphatidylinositol : evidence for the enzymatic incorporation of a fraudulent cyclitol into the phosphatidylinositol cycle : a mass spectrometry study / David C. Baker, Stephen C. Johnson, James D. Moyer, Nancy Malinowski, Frank Tagliaferri, and Albert Tuinman.