Comparative Diagnostic Pharmacology: Clinical and Research Applications in Living-System Models

Comparative Diagnostic Pharmacology: Clinical and Research Applications in Living-System Models is the first evidence-based reference text devoted exclusively to the subject of applying pharmaceutical and biopharmaceutical agents as diagnostic probes in clinical medicine and investigative research.This unique and groundbreaking book is a versatile guide for clinicians and researchers interested in using pharmacologic agents to: Diagnose disease Assess physiological processes Identify the appropriateness of a therapeutic agent Determine appropriate dosing for therapeutic use.Extensively referenced and organized by major body systems, individual topics are listed in an evidence-based format according to specific disease processes or physiological processes of interest. Each entry also includes information on the mechanism of action, administration, and diagnostic interpretation.Descriptions have been provided for the application of diagnostic pharmaceuticals to assess a wide spectrum of diseases and physiological processes relevant to the fields of veterinary and human medicine. Comparative Diagnostic Pharmacology is useful not merely for pharmaceutical-oriented research investigations, but it will also prove invaluable for the monitoring and evaluation of physiological responses and disease processes in animal models.Content: Chapter 1 Cardiovascular System (pages 5–60): Chapter 2 Central Nervous System (pages 61–127): Chapter 3 Endocrine System (pages 129–177): Chapter 4 Gastrointestinal System (pages 179–220): Chapter 5 Hematopoietic System (pages 221–266): Chapter 6 Hepatic System (pages 267–335): Chapter 7 Integumentary System (pages 337–339): Chapter 8 Musculoskeletal System (pages 341–349): Chapter 9 Reproductive System (pages 351–354): Chapter 10 Renal and Urinary Systems (pages 355–373): Chapter 11 Respiratory System (pages 375–403): Chapter 12 Cancer/Neoplastic Disease (pages 407–424): Chapter 13 Genetics and Nucleic Acids (pages 425–438): Chapter 14 Inflammation, Infection, and Sepsis (pages 439–453): Chapter 15 Metabolism, Electrolytes, and Hypoxia (pages 455–470): Chapter 16 Fluorescent and Pigment Dye Reagents (pages 473–516): Chapter 17 Magnetic Resonance Imaging (MRI) (pages 517–567): Chapter 18 Nuclear Planar Scintigraphy (pages 569–675): Chapter 19 Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) (pages 677–729): Chapter 20 Radiographic Image?Enhancing Agents (pages 731–764): Chapter 21 Ultrasonography (pages 765–808): Chapter 22 Biological and Synthetic Delivery Modalities (pages 811–905):