Cell Entry by Non-Enveloped Viruses (Current Topics in Microbiology and Immunology, Volume 343) By John E. Johnson
2010 | 240 Pages | ISBN: 3642133312 | PDF | 4 MB
2010 | 240 Pages | ISBN: 3642133312 | PDF | 4 MB
The means by which non-enveloped viruses penetrate cellular membranes during cell entry remain poorly defined. Recent findings indicate several members of this group share a common mechanism of membrane penetration in which the virus particle undergoes programmed conformational changes, leading to capsid disassembly and release of small membrane-interacting peptides. A complete understanding of host cell entry by this minimal system will help elucidate the mechanisms of non-enveloped virus membrane penetration in general