Lead-Seeking Approaches By Kevin D. Freeman-Cook, Daniel W. Kung (auth.), Matthew M. Hayward (eds.)
2010 | 217 Pages | ISBN: 3642010741 | PDF | 2 MB
2010 | 217 Pages | ISBN: 3642010741 | PDF | 2 MB
Christopher A. Lipinski: Overview of Hit to Lead: The Medicinal Chemist’s Role from HTS Retest to Lead Optimization Hand OffJeff W. Paslay • John E. Morin • Richard K. Harrison: High Throughput Screening in the Twenty - First CenturyJack Andrew Bikker • Lakshmi S.Narasimhan: Lead Discovery Using Virtual Screening Maurizio Pellecchia: NMR Spectroscopy in Fragment Based Drug DesignKevin D. Freeman-Cook • Daniel W. Kung: Hit Triage – Medicinal Chemistry Strategies to Improve the Odds of Success in DiscoveryJohn W. Ellingboe • Adam M. Gilbert: Lead Identification