Schizophrenia, Second Edition

Schizophrenia is one of the most complex and puzzling diseases to affect mankind. It is the most common of the severe mental illnesses (psychoses) with an estimated prevalence of 0.5 - 1% in the general population and accounts for a very large portion of the day to day workload of the average psychiatrist. 50% of long-term psychiatric patients in mental hospitals are schizophrenic. There is a great deal of controversy about the causes, diagnosis and treatment of schizophrenia with the consequence that a huge amount of research is carried out in the field by psychiatrists, psychologists, neuroscientists and pharmacologists. For the average practising psychiatrist seeing schizophrenics on a regular basis, making sense of the vast body of information on the subject and filtering out what is of clinical relevance can be very difficult. There is a constant stream of new drugs emerging and the newer generation of drugs (the so-called atypicals) is very effective, but often expensive. The Editors (one American and one British) are both highly respected clinical psychiatrists who are probably the leading experts on schizophrenia from their respective countries and jointly have published almost 150 papers on the subject. They have brought together a strong group of contributors from the USA, UK and Europe to produce what will be an essential reference for the trainee and practising psychiatrist. The book consists of four sections; descriptive aspects, causative aspects, physical treatments and psychological/behavioural/social treatments. There will be discussion of the theoretical controversies over symptomatology, classification and aetiology, the relationship of schizophrenia to the other psychoses, the significance of positive and negative symptoms and pre-morbid personality. There will be chapters on organic models of schiziophrenia, neurodevelopmental, genetic and structural studies and the role of high-expressed emotion. The final section will cover social and environmental treatment, the role of the families of schizophrenics and the psychoanalytical therapies. There is a new chapter on the patient's perspective written by a former patient. Content: Chapter 1 Concepts and Classification of Schizophrenia (pages 1–14): J.K. Wing and N. AgrawalChapter 2 Descriptive Psychopathology (pages 15–24): J. CuttingChapter 3 The Symptoms of Schizophrenia (pages 25–33): R.L.M. Fuller, S.K. Schultz and N.C. AndreasenChapter 4 Child and Adolescent Onset Schizophrenia (pages 34–53): C. HollisChapter 5 Atypical Psychotic Disorders (pages 54–67): C.B. Pull, J.M. Cloos and N.V. MurthyChapter 6 Late?Onset Schizophrenia (pages 68–79): R. Howard and D.V. JesteChapter 7 The Schizophrenia Spectrum Personality Disorders (pages 80–100): K. O'Flynn, J. Gruzelier, A. Bergman and L.J. SieverChapter 8 Course and Outcome of Schizophrenia (pages 101–141): H. Hafner and W. an der HeidenChapter 9 Depression and Schizophrenia (pages 142–167): S.G. Siris and C. BenchChapter 10 Neurocognitive Deficits in Schizophrenia (pages 168–184): T.E. Goldberg, A. David and J.M. GoldChapter 11 The Secondary Schizophrenias (pages 185–202): T.M. Hyde and S.W. LewisChapter 12 The Epidemiological Horizon (pages 203–231): A. JablenskyChapter 13 Risk Factors for Schizophrenia: From Conception to Birth (pages 232–250): J.J. McGrath and R. M. MurrayChapter 14 Genetics and Schizophrenia (pages 251–276): B. Riley, P.J. Asherson and P. McGuffinChapter 15 Intermediate Phenotypes in Genetic Studies of Schizophrenia (pages 277–297): M.F. Egan, M. Leboyer and D.R. WeinbergerChapter 16 Electrophysiology of Schizophrenia (pages 298–309): D.F. Salisbury, S. Krljes and R.W. McCarleyChapter 17 Neuropathology of Schizophrenia (pages 310–325): P.J. Harrison and D.A. LewisChapter 18 Schizophrenia as a Neurodevelopmental Disorder (pages 326–348): D.R. Weinberger and S. MarencoChapter 19 The Neurochemistry of Schizophrenia (pages 349–364): B. Moghaddam and J.H. KrystalChapter 20 Dopamine Transmission in the Schizophrenic Brain (pages 365–387): M. LaruelleChapter 21 Animal Models of Schizophrenia (pages 388–402): B.K. Lipska and D.R. WeinbergerChapter 22 Brain Imaging in Schizophrenia (pages 403–417): P. Liddle and C. PantelisChapter 23 The Neuroscience and Clinical Psychopharmacology of First? and Second?Generation Antipsychotic Drugs (pages 419–441): J.L. Waddington, S. Kapur and G.J. RemingtonChapter 24 Acute Pharmacological Treatment of Schizophrenia (pages 442–473): S. Miyamoto, T.S. Stroup, G.E. Duncan, A. Aoba and J.A. LiebermanChapter 25 Maintenance Treatment (pages 474–488): S.R. Marder and D.A. WirshingChapter 26 Treatment?Resistant Schizophrenia (pages 489–516): T.R.E. Barnes, P. Buckley and S.C. SchulzChapter 27 Electroconvulsive Therapy and Schizophrenia (pages 517–551): H.A. SackeimChapter 28 Neuroleptic?Induced Acute Extrapyramidal Syndromes and Tardive Dyskinesia (pages 552–572): V.S. Mattay and D.E. CaseyChapter 29 Non?Neurological Side?Effects of Antipsychotic Drugs (pages 573–588): D.C. Goff and R.I. ShaderChapter 30 Schizophrenia and Violence (pages 589–612): P.J. Taylor and S.E. EstroffChapter 31 Schizophrenia and Psychosocial Stresses (pages 613–636): P.E. Bebbington and E. KuipersChapter 32 Psychiatric Rehabilitation (pages 637–656): T.K.J. Craig, R.P. Liberman, M. Browne, M.J. Robertson and D. O'FlynnChapter 33 Psychological Treatments for Schizophrenia (pages 657–687): B.V. Martindale, K.T. Mueser, E. Kuipers, T. Sensky and L. GreenChapter 34 Mental Health Services (pages 688–700): M. Muijen, F. Holloway and H. GoldmanChapter 35 Psychosis and Recovery: Some Patients' Perspectives (pages 701–712): Peter Chadwick, Robert Lundin, Grace Brown, Alison McPartlin, Claire Brookman and Janey AntoniouChapter 36 Economics of the Treatment of Schizophrenia (pages 713–723): S.M. Essock, L.K. Frisman and N.H. Covell