Multiple Sclerosis: Perspectives in Treatment and Pathogenesis

Multiple sclerosis: Perspectives in Treatment and Pathogenesis, contributed by 27 experts from around the globe, is a valuable reference for physicians, healthcare professionals, students and basic scientists who are dedicated to multiple sclerosis research and patient care. The book provides a modern perspective on treatment and pathogenesis of multiple sclerosis under two sections. Section I outlines how genetics predisposes a person to multiple sclerosis. This is followed by a detailed description of the prevalence of multiple sclerosis in Europe, and the challenges of treating pediatric patients, especially the strengths and weaknesses of steroid treatment. A major symptom of multiple sclerosis is chronic pain. A dedicated chapter discusses the treatment strategies for chronic pain. Is vitamin D a potential cure? One of the chapters provide a compelling argument for vitamin D supplementation as an adjunctive therapy, followed by a case for stem-cell therapy to reverse the progression of multiple sclerosis. Section II focuses on new and exciting theories on the pathogenesis of multiple sclerosis. Basic science and clinical data are presented on three novel thematic areas including primary neuroinflammation, oxidative stress pathways, and the role of endogenous opioids and their receptors in multiple sclerosis.