Challenges in Prostate Cancer, Second Edition

Prostate cancer continues to be a major threat to men's health, the second most common cancer in men, in many countries. Therefore it is increasingly important that those faced with difficult clinical questions make the right decisions. Since the first volume was published in 2000, many debates persist but new controversies have also emerged, reflected in the chapters of this new volume. New authors have been recruited to give their insight into newer areas of this controversial topic. Challenges in prostate cancer provides a series of state-of-the-art review articles, each of which addresses and answers a contentious question. It includes chapters on medical and surgical management of all stages of prostate cancer, clinical investigation, epidemiology, clinical trials and basic scientific research and covers issues such as the genetic basis of cancer, clinical economics and influence. The authors have used their expertise to distil the available evidence into practical advice to be used by busy urologists in their day-to-day practice. And as well as being an overview of current practice many chapters attempt to give insights into the future direction of prostate cancer research and clinical management.Content: Chapter 1 An Update on Biotechnology in the Assessment of Prostate Cancer (pages 1–16): Tim Lane, Jon Strefford and Tim OliverChapter 2 What Can we Learn from Breast Cancer? (pages 17–25): Ludger Barthelmes and Christopher A. GateleyChapter 3 New Serum Markers for Prostate Cancer (pages 26–39): Bernhard Brehmer, Antonios Makris and Gerhard JakseChapter 4 The History of Tissue Recombination Technology: Current and Future Research (pages 40–52): Kenichiro Ishii and Simon HaywardChapter 5 Why we Cannot use the Results of Non?Randomised Trials to Inform us About Treatment for Early Prostate Cancer? (pages 53–61): Malcolm Mason and John StaffurthChapter 6 Equivocal PSA Results and Free Total PSA Ratio (pages 63–75): Bob Djavan, Michael Dobrovits and Michael MarbergerChapter 7 Equivocal Prostate Needle Biopsies (pages 76–84): Murali Varma and David GriffithsChapter 8 Prostate Biopsy: How Many Cores and Where From? (pages 85–96): Richard ClementsChapter 9 Counselling Patients with Early Prostate Cancer (pages 97–111): Gail Beese and Christopher EdmundsChapter 10 The Role of Pelvic Node Dissection in Prostate Cancer (pages 112–123): Owen Niall and Jamie KearsleyChapter 11 Laparoscopic Radical Prostatectomy (pages 125–136): Mark WrightChapter 12 Endocrine Therapy for Prostate Cancer: The Latest (pages 137–152): A. Goyal and W. BowsherChapter 13 The Role of Conservative Policies in the Treatment of Prostate Cancer (pages 153–166): Stijn de Vries, Christopher Bangma and Fritz SchroderChapter 14 Complementary and Alternative Therapies for Prostate Cancer (pages 167–177): Gary Deng and Barrie CassilethChapter 15 Radical Prostatectomy After Radical Radiotherapy (pages 179–192): Amir KaisaryChapter 16 Treatment of Renal Impairment Secondary to Locally Advanced Prostate Cancer (pages 193–208): Paul Jones and Neil FennChapter 17 Open Radical Prostatectomy: How Can Intra?Operative, Peri?Operative and Post?Operative Complications be Prevented? (pages 209–225): Robert P. Myers, R. Houston Thompson, Stephen M. Schatz and Michael L. BluteChapter 18 Documenting Prostate Cancer: Epidemiology and Treatment (pages 226–245): Leslie MoffatChapter 19 Trends in Prostate Cancer Incidence and Mortality (pages 246–257): Steven Oliver, Rhidian Hurle and Owen HughesChapter 20 Chemotherapy in Prostate Cancer (pages 258–272): Jason Lester and Emma Hudson