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    3. Group Sequential Methods with Applications to Clinical Trials by Bruce W. Turnbull

    Group Sequential Methods with Applications to Clinical Trials by Bruce W. Turnbull

    Posted By: BUGSY
    Date: 5 Jun 2015 18:32:10
    Group Sequential Methods with Applications to Clinical Trials by Bruce W. Turnbull

    Group Sequential Methods with Applications to Clinical Trials (Chapman & Hall/CRC Interdisciplinary Statistics) by Bruce W. Turnbull
    English | 2000 | ISBN: 0849303168 | 392 Pages | PDF | 1 MB

    Group sequential methods answer the needs of clinical trial monitoring committees who must assess the data available at an interim analysis. These interim results may provide grounds for terminating the study-effectively reducing costs-or may benefit the general patient population by allowing early dissemination of its findings. Group sequential methods provide a means to balance the ethical and financial advantages of stopping a study early against the risk of an incorrect conclusion.
    Group Sequential Methods with Applications to Clinical Trials describes group sequential stopping rules designed to reduce average study length and control Type I and II error probabilities.

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