ENHANZE® Drug Delivery Technology : Advancing Subcutaneous Drug Delivery Using Recombinant Human Hyaluronidase PH20
ENHANZE® Drug Delivery Technology : Advancing Subcutaneous Drug Delivery Using Recombinant Human Hyaluronidase PH20
by David W. Kang and Renee Tannenbaum
English | 2022 | ISBN: 3318070769 | 106 Pages | True PDF | 10.4 MB
by David W. Kang and Renee Tannenbaum
English | 2022 | ISBN: 3318070769 | 106 Pages | True PDF | 10.4 MB
‘ENHANZE® drug delivery technology: Advancing subcutaneous drug delivery using recombinant human hyaluronidase PH20’ provides readers with in-depth information on the potential benefits and challenges of subcutaneous (SC) drug delivery, the biology of hyaluronan and hyaluronidases in the SC space, and a comprehensive overview on the history of hyaluronidases and the development of recombinant human hyaluronidase PH20 (rHuPH20). Current applications of rHuPH20 as well as approved biotherapeutics utilizing HuPH20-facilitated SC drug delivery are summarized, and the underlying non-clinical and clinical development approaches are introduced as a basis for future application to biologics in various disease areas.