New Frontiers in Asymmetric Catalysis by Koichi Mikami
New Frontiers in Asymmetric Catalysis by Koichi Mikami
Wiley-Interscience; 1 edition | May 4, 2007 | English | ISBN: 0471680265 | 435 pages | PDF | 13 MB
Wiley-Interscience; 1 edition | May 4, 2007 | English | ISBN: 0471680265 | 435 pages | PDF | 13 MB
A compilation of recent advances and applications in asymmetric catalysis
The field of asymmetric catalysis has grown rapidly and plays a key role in drug discovery and pharmaceuticals. New Frontiers in Asymmetric Catalysis gives readers a fundamental understanding of the concepts and applications of asymmetric catalysis reactions and discusses the latest developments and findings. With contributions from preeminent scientists in their respective fields, it covers:
* "Rational" ligand design, which is critically dependent on the reaction type (reduction, oxidation, and C-C bond formation)
* Recent findings on activation of C-H bonds, C-C bonds, and small molecules (C=O, HCN, RN=C, and CO2) and the latest developments on C-C bond reorganization, such as metathesis
* Advances in "chirally economical" non-linear phenomena, racemic catalysis, and autocatalysis
* Some of the recent discoveries that have led to a renaissance in the field of organocatalysis, including the development of chiral Br?nstead acids and Lewis acidic metals bearing the conjugate base of the Br?nstead acids as the ligands and the chiral bi-functional acid/base catalysts