Human Challenge Studies for Vaccine Development
Human Challenge Studies for Vaccine Development
English | 2024 | ISBN: 303163117X | 663 Pages | PDF EPUB (True) | 17 MB
English | 2024 | ISBN: 303163117X | 663 Pages | PDF EPUB (True) | 17 MB
This volume offers insights into human challenge studies, where adult volunteers are deliberately infected with a pathogen of interest. These studies can broaden our knowledge on infections that have a rather low natural infection rate, but still bear a great threat to global health. The authors also present instances, where no suitable animal model is available to help understand human immune responses to a specific pathogen. The recent SARS-CoV-2 pandemic is another example, where studies that are directly conducted in humans, could save valuable time.