Annual Update in Intensive Care and Emergency Medicine 2019

Part I. Precision medicine.- Precision delivery in critical care: balancing prediction and personalization.- Precision medicine in the ICU: identifying opportunities and overcoming barriers.- Part II. Acute Respiratory Failure - ARDS.- Acute respiratory failure in the oncologic patient: new era, new issues.- Universal low tidal volume: early initiation of low tidal volume ventilation in patients with and without ARDS.- Recruitment maneuvers and higher PEEP, the so-called open lung concept, in patients with ARDS: rationale, limitations and indications.- ARDS in obese patients: specificities and management.- Part III. Extracorporeal Respiratory Support.- ECMO after EOLIA: the evolving role of extracorporeal support in ARDS.- Physiological and technical consideration of extracorporeal CO2 removal.- Part IV. Cardiac arrest.- Cardiac arrest in the ICU.- Targeted temperature management after cardiac arrest: where are we now?.- Part V. Cardiac Function.- Left diastolic function in critically ill mechanically ventilated patients.- The effects of disease and treatment on ventriculo-arterial coupling: implications for long term care.-Part VI. Shock.- Lactate in critically ill patients: at the crossroad between perfusion and metabolism.- Mechanical circulatory support devices for cardiogenic shock: state of the Art.- Sodium thiosulfate: a new player for circulatory shock and ischemia/reperfusion injury?.- Part VII. Hemodynamic Monitoring.- Continuous non-invasive monitoring of cardiac output and lung volume based on CO2 kinetics.- Should we abandon measuring SvO2 or ScvO2 in septic patients?.- Perioperative hemodynamic monitoring: MERCI to predict economic impact.- The pulmonary artery catheter in the management of the high risk surgical patient: an irreplaceable tool!.- Part VIII. Intravenous Fluids.- Resuscitation fluid choices to preserve the endothelial glycocalyx.-Should albumin be the colloid of choice for fluid resuscitation in hypovolemic patients?.- What the intensive care physician should know about the transurethral resection (TUR) syndrome.- Relationship between central venous pressure and acute kidney injury in critically ill patients.- Fluid management in acute kidney injury.- Part IX. Altered Renal Function.- New insights into renal microcirculation in sepsis-induced acute kidney injury.- Atypical sepsis-associated acute kidney injury.- Latest developments in perioperative acute kidney injury.- Diagnostic implications of creatinine and urea metabolism in critical illness.- Renal replacement therapy during septic renal dysfunction.- Acid-base disorders and regional citrate anticoagulation with continuous renal replacement therapy.- Acute kidney injury and delirium: kidney-brain cross-talk.- Part X. The Neurological Patient.- Brain ultrasound in the non-neurocritical care setting.- Brain fog: Are clearer skies on the horizon? A review on perioperative neurocognitive disorders.- Uncovering consciousness in unresponsive ICU patients: technical, medical and ethical considerations.- Part XI. Infection and Antibiotics.- From influenza-induced acute lung injury to multiorgan failure.- Multidrug resistant Gram-negative bacteria in community-acquired pneumonia.- Lights and shadows of antibiotics recently approved and in advanced development for critically ill patients.- Target-controlled infusion in the ICU: an opportunity to optimize antibiotic therapy.- Antimicrobial stewardship in sepsis.- Part XII. Sepsis.- Heterogeneity in sepsis: new biological evidence with clinical applications.- The role of mitochondrial dysfunction in sepsis: what is new?.- Potential harm related to fluid resuscitation in sepsis.- Extracorporeal cytokine removal in septic shock.- Part XIII. Iron Metabolism.- Transferrin as a possible treatment of anemia of inflammation in the critically ill.- Iron metabolism: an emerging therapeutic target in critical illness.- Part XIV. Extremes of Age.- Functional impairments in pe