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    Photopolymerizable Porous Polyorganophosphazenes: Degradable Matrices for Tissue Engineering [Repost]

    Posted By: ChrisRedfield
    Photopolymerizable Porous Polyorganophosphazenes: Degradable Matrices for Tissue Engineering [Repost]

    Tamara Bernadette Aigner - Photopolymerizable Porous Polyorganophosphazenes: Degradable Matrices for Tissue Engineering
    Published: 2015-03-16 | ISBN: 3658093196 | PDF | 75 pages | 1.78 MB


    Tamara Bernadette Aigner designed a set of biocompatible and biodegradable poly(organophosphazenes). In order to tailor their biological and chemical properties, she further modified these macromolecules by adding functional moieties via thiol-ene chemistry. The author used the same photochemistry for crosslinking to obtain a mechanically stable network. She further altered the degradation rate of the matrix as well as the mechanical properties by adding blending agents and created a porous matrix, which is necessary for cell invasion and communication, by a newly developed photocrosslinking particulate-leaching method. Thus, a modular hybrid system was established which is able to adapt to different microenvironments based upon tissue type.

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