Kewal K. Jain - Textbook of Personalized Medicine
Published: 2009-09-17 | ISBN: 1441907688 | PDF | 430 pages | 10 MB
Personalized medicine is the concept that selection of a treatment should be tailored according to the individual patient’s specific characteristics, including age, gender, height/weight, ethnicity, diet, and environment , versus a decision based on ‘standards of care’ derived by averaging responses across large cohorts of individuals in clinical trials. This alternate approach has only been possible as a result of the translation and integration of several new technologies in clinical care. As the first definitive work on this topic, Textbook of Personalized Medicine reviews the fundamentals and development of personalized medicine, and subsequent adoptions of the concepts by the biopharmaceutical industry and the medical profession. It also discusses examples of applications in key therapeutic areas, as well as ethical and regulatory issues. The textbook will serve as a convenient source of information for physicians, scientists, decision makers in the biopharmaceutical and healthcare industries, and interested members of the public.
Contents:
Basics of Personalized Medicine
Molecular Diagnostics as Basis of Personalized Medicine
Role of Biomarkers in Personalized Medicine
Pharmacogenetics
Pharmacogenomics
Pharmacoproteomics
Metabolomics
Personalized Biological Therapies
Development of Personalized Therapy
Personalized Therapy of Cancer
Personalized Management of Cardiovascular Disorders
Personalized Management of Miscellaneous Disorders
Personalized preventive medicine
Organization of Personalized Medicine
Ethical and Regulatory Aspects of Personalized Medicine
Economics of Personalized Medicine
Future of Personalized Medicine