Computational Modeling of Drugs Against Alzheimer's Disease (Neuromethods)
Computational Modeling of Drugs Against Alzheimer's Disease (Neuromethods) by Kunal Roy
English | 2 Nov. 2017 | ISBN: 1493974033 | 664 Pages | PDF | 14.07 MB
English | 2 Nov. 2017 | ISBN: 1493974033 | 664 Pages | PDF | 14.07 MB
This volume describes different computational methods encompassing ligand-based approaches (QSAR, pharmcophore), structure-based approaches (homology modeling, docking, molecular dynamics simulation), and combined approaches (virtual screening) with applications in anti-Alzheimer drug design. Different background topics like molecular etiologies of Alzheimer’s disease, targets for new drug development, and different cheminformatic modeling strategies are covered for completeness. Special topics like multi-target drug development, natural products, protein misfolding, and nanomaterials are also included in connection with computational modeling of anti-Alzheimer drug development. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.