Peter D. Adams, John M. Sedivy, "Cellular Senescence and Tumor Suppression"
English | 2010 | ISBN: 1441910743 | PDF | pages: 274 | 4.8 mb
English | 2010 | ISBN: 1441910743 | PDF | pages: 274 | 4.8 mb
As cells mature they naturally stop dividing and enter a period called senescence. But cellular senescence can also be induced prematurely by certain oncogenes involved in cancer development. Cellular senescence, a growth-arrest program that limits the lifespan of mammalian cells and prevents unlimited cell proliferation, is attracting considerable interest because of its links to tumor suppression.