Ocular Drug Delivery Systems: Barriers and Application of Nanoparticulate Systems

Drug discovery for ocular diseases has taken great strides in the last two decades. From cornea to choroid, new drugs have been formulated to address a great variety of ocular diseases. Yet, without good drug delivery systems, these drugs are less effective than they could be, possibly even ineffective or could cause serious side effects. Ocular Drug Delivery Systems: Barriers and Application of Nanoparticulate Systems presents research on the development of currently marketed devices and recent trends in the topical delivery of drugs to the posterior of the eye.

With contributions from leading pharmaceutical researchers and industry experts, eye researchers, surgeons, pharmacologists from academia, the National Eye Institute, and leading ophthalmic companies such as Pfizer, Allergan, and Novartis, the book not only presents the state of the art in the use of nanoparticles in ocular drug delivery systems but sets the stage for future developments.

This volume gives both a current evaluation and a future roadmap for developments in ocular drug delivery. The subjects range from biological needs to material challenges and finally to clinical applications for improving drug delivery for conditions where treatments already exist and for unmet needs where effective drugs may be available but yet need a safe, efficient, and efficacious delivery vehicle.