Transporters and Drug-Metabolizing Enzymes in Drug Toxicity
Transporters and Drug-Metabolizing Enzymes in Drug Toxicity by Albert P. Li
English | ISBN: 1119170842 | 528 pages | EPUB | July 21, 2021 | 12 Mb
English | ISBN: 1119170842 | 528 pages | EPUB | July 21, 2021 | 12 Mb
This book provides a comprehensive and up-to-date coverage of the relationship between drug metabolism enzymes and transporters on drug toxicity, along with methods to investigate their role on adverse drug reactions.
Unites both the metabolism and transporter components of drug toxicity – two aspects not normally connected and the latter often neglected
Familiarizes readers with the mechanism and species differences in drug metabolizing enzymes and transporters
Discusses promising approaches to accurately predict human drug toxicity via the incorporation of human drug metabolism in toxicity evaluation