Coursera - Drugs and the Brain
WEBRip | English | MP4 + work files | 960 x 540 | AVC ~140 kbps | 29.970 fps
AAC | 64 Kbps | 44.1 KHz | 2 channels | Subs: English | ~14 hours | 1.72 GB
Genre: eLearning Video / Neuroscience
WEBRip | English | MP4 + work files | 960 x 540 | AVC ~140 kbps | 29.970 fps
AAC | 64 Kbps | 44.1 KHz | 2 channels | Subs: English | ~14 hours | 1.72 GB
Genre: eLearning Video / Neuroscience
The neuroscience of drugs for therapy, for prevention, and for recreation. Drug addiction and drug abuse. You learn the prospects for new generations of medications in neurology, psychiatry, aging, and treatment of substance abuse.About the Course
What happens in the body when a person smokes a cigarette? After several weeks of smoking? When a person takes antidepressant or antipsychotic medication? A drug for pain, migraine, or epilepsy? A recreational drug? Neuroscientists are beginning to understand these processes. You’ll learn how drugs enter the brain, how they act on receptors and ion channels, and how “molecular relay races” lead to changes in nerve cells and neural circuits that far outlast the drugs themselves. “Drugs and the Brain” also describes how scientists are gathering the knowledge required for the next steps in preventing or alleviating Parkinson’s, Alzheimer’s, schizophrenia, and drug abuse.
Course Syllabus
Week 1. Beginning 4 January 2014
Introduction and summary of the course. What is a drug? Types of drug molecules. Drug entry into nervous system. Drug receptors. Introduction to mammalian brains. Botulinum toxin. Origin of the resting potential. Electrophysiology.
Week 2. Beginning 11 January
Drugs activate ion channels. Drugs block ion channels. Drugs activate and block G protein pathways.
Week 3. Beginning 18 January
Drugs block neurotransmitter transporters. Pharmacokinetics. Recreational drugs
Week 4. Beginning 25 January
Drug addiction and Drug abuse.Nicotine Addiction.Opiate Addiction.
Week 5. Beginning 1 February
Drugs for neurodegenerative diseases: Alzheimer's disease, Parkinson's disease.
Week 6. Beginning 8 February
Drugs for epilepsy and migraine. Drugs for anxiety.
Week 7.Beginning 15 February
Drugs for psychiatric diseases: Depression, Bipolar Disorder, Schizophrenia. Prospects for better drugs.
Recommended Background
Neuroscience, the most interdisciplinary science of the 21st century, receives inputs from many other fields of science, medicine, clinical practice, and technology. Previous exposure to one or more of the subjects listed in "Suggested Readings" will provide a good vantage point, as we introduce material from these subjects.
Content:
Week_1._Organization_and_Overview_2_miniLectures
Week_1._Introductory_concepts_9_miniLectures
Week_2._Dose-response_Relations_3_miniLectures
Week_2._Synapses_5_miniLectures
Week_2._Channel_Blockers_2_miniLectures
Week_3._G_protein_pathways_5_miniLectures
Week_3._Neurotransmitter_transporters_2_miniLectures
Week_3._Recreational_Drugs_3_miniLectures
Week_4._Nicotine_Addiction_5_miniLectures
Week_4._Opiate_Addiction_4_miniLectures
Week_5._Alzheimers_Disease_3_miniLectures
Week_5._Parkinsons_Disease_5_miniLectures
Week_6._Pharmacokinetics_and_Metabolism_5_miniLectures
Week_6._Classifying_Psychiatric_Diseases_1_miniLecture
Week_6._Anxiety_Disorders_4_miniLectures
Week_7._Drugs_for_Major_Depressive_Disorder_4_miniLectures
Week_7._Drugs_for_Bipolar_Disorder_3_miniLecture
Week_7._Drugs_for_Schizophrenia_4_miniLectures
Week_7._Wrap-Up_1_miniLecture
also You can watch my other last: Coursera-posts
General
Complete name : 02_2_Inhibitory_G_Proteins_and_their_Effectors_7-10.mp4
Format : MPEG-4
Format profile : Base Media
Codec ID : isom
File size : 10.9 MiB
Duration : 7mn 10s
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Video
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Format/Info : Advanced Video Codec
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Format settings, CABAC : Yes
Format settings, ReFrames : 4 frames
Codec ID : avc1
Codec ID/Info : Advanced Video Coding
Duration : 7mn 10s
Bit rate : 140 Kbps
Width : 960 pixels
Height : 540 pixels
Display aspect ratio : 16:9
Frame rate mode : Constant
Frame rate : 29.970 fps
Color space : YUV
Chroma subsampling : 4:2:0
Bit depth : 8 bits
Scan type : Progressive
Bits/(Pixel*Frame) : 0.009
Stream size : 7.18 MiB (66%)
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Language : English
Audio
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Format : AAC
Format/Info : Advanced Audio Codec
Format profile : LC
Codec ID : 40
Duration : 7mn 10s
Bit rate mode : Constant
Bit rate : 64.0 Kbps
Channel(s) : 2 channels
Channel positions : Front: L R
Sampling rate : 44.1 KHz
Compression mode : Lossy
Delay relative to video : -800ms
Stream size : 3.29 MiB (30%)
Language : English
Complete name : 02_2_Inhibitory_G_Proteins_and_their_Effectors_7-10.mp4
Format : MPEG-4
Format profile : Base Media
Codec ID : isom
File size : 10.9 MiB
Duration : 7mn 10s
Overall bit rate : 212 Kbps
Writing application : Lavf55.10.100
Video
ID : 1
Format : AVC
Format/Info : Advanced Video Codec
Format profile : Main@L3.1
Format settings, CABAC : Yes
Format settings, ReFrames : 4 frames
Codec ID : avc1
Codec ID/Info : Advanced Video Coding
Duration : 7mn 10s
Bit rate : 140 Kbps
Width : 960 pixels
Height : 540 pixels
Display aspect ratio : 16:9
Frame rate mode : Constant
Frame rate : 29.970 fps
Color space : YUV
Chroma subsampling : 4:2:0
Bit depth : 8 bits
Scan type : Progressive
Bits/(Pixel*Frame) : 0.009
Stream size : 7.18 MiB (66%)
Writing library : x264 core 129 r2230 1cffe9f
Encoding settings : cabac=1 / ref=3 / deblock=1:0:0 / analyse=0x1:0x111 / me=hex / subme=7 / psy=1 / psy_rd=1.00:0.00 / mixed_ref=1 / me_range=16 / chroma_me=1 / trellis=1 / 8x8dct=0 / cqm=0 / deadzone=21,11 / fast_pskip=1 / chroma_qp_offset=-2 / threads=12 / lookahead_threads=2 / sliced_threads=0 / nr=0 / decimate=1 / interlaced=0 / bluray_compat=0 / constrained_intra=0 / bframes=3 / b_pyramid=2 / b_adapt=1 / b_bias=0 / direct=1 / weightb=1 / open_gop=0 / weightp=2 / keyint=250 / keyint_min=25 / scenecut=40 / intra_refresh=0 / rc_lookahead=40 / rc=crf / mbtree=1 / crf=28.0 / qcomp=0.60 / qpmin=0 / qpmax=69 / qpstep=4 / ip_ratio=1.40 / aq=1:1.00
Language : English
Audio
ID : 2
Format : AAC
Format/Info : Advanced Audio Codec
Format profile : LC
Codec ID : 40
Duration : 7mn 10s
Bit rate mode : Constant
Bit rate : 64.0 Kbps
Channel(s) : 2 channels
Channel positions : Front: L R
Sampling rate : 44.1 KHz
Compression mode : Lossy
Delay relative to video : -800ms
Stream size : 3.29 MiB (30%)
Language : English
Screenshots
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