"Pancreatic Cancer: Molecular Mechanism and Targets" ed. by Sanjay K. Srivastava

This book provides the reader with an overall understanding of the biology of pancreatic cancer, hereditary, complex signaling pathways and alternative therapies. The book explains nutrigenomics and epigenetics mechanisms such as DNA methylation, which may explain the etiology or progression of pancreatic cancer. Book also summarizes the molecular control of oncogenic pathways such as K-Ras and KLF4.

Contents
Preface
1 Risk Factors in Pancreatic Cancer
2 Epigenetics and Pancreatic Cancer: The Role of Nutrigenomics
3 Characterization of the Molecular Genetic Mechanisms that Contribute to Pancreatic Cancer Carcinogenesis
4 Pancreatic Cancer: Current Concepts in Invasion and Metastasis
5 Nitric Oxide Regulates Growth Factor Signaling in Pancreatic Cancer Cells
6 Kinase Activity is Required for Growth Regulation but not Invasion Suppression by Syk Kinase in Pancreatic Adenocarcinoma Cells
7 New Targets for Therapy in Pancreatic Cancer
3 Failure of Pancreatic Cancer Chemotherapy: Consequences of Drug Resistance Mechanisms
9 Prevention of Pancreatic Cancer
10 Vitamin D for the Prevention and Treatment of Pancreatic Cancer
11 Molecular Targets of Benzyl Isothiocyanates in Pancreatic Cancer
12 The Potential Role of Curcumin for Treatment of Pancreatic Cancer
13 Immunotherapy for Pancreatic Cancer
14 The Role of Mesothelin in Pancreatic Cancer
15 Establishment of Primary Cell Lines in Pancreatic Cancer
16 Disruption of Cell Cycle Machinery in Pancreatic Cancer
17 Glycans and Galectins: Sweet New Approaches in Pancreatic Cancer Diagnosis and Treatment
18 The Adhesion Molecule L1CAM as a Novel Therapeutic Target for Treatment of Pancreatic Cancer Patients?
19 p53 Re-Activating Small Molecule Inhibitors for the Treatment of Pancreatic Cancer
20 Toll-Like Receptors as Novel Therapeutic Targets for the Treatment of Pancreatic Cancer
21 rb7 - A Newly Emerging Target in Pancreatic Cancer
22 Human Telomerase Reverse Transcriptase Gene Antisense Oligonucleotide Increases the Sensitivity of Pancreatic Cancer Cells to Gemcitabine In Vitro