"Muscle Cell and Tissue" ed. by Kunihiro Sakuma

This book offers a wide range of topics such as stem cells, cell culture, biomaterials, epigenetics, therapeutics, and the creation of tissues and organs. Novel applications for cell and tissue engineering including cell therapy, tissue models, and disease pathology modeling are discussed. The book also deals with the functional role of autophagy in modulating muscle homeostasis and molecular mechanism regulating skeletal muscle mass.

The book can be interesting for graduate students, postdocs, teachers, physicians, and for executives in biotech and pharmaceutical companies, as well as researchers in the fields of molecular biology and regenerative medicine.

Contents
Preface
1 Vascular Smooth Muscle as a Therapeutic Target in Disease Pathology
2 Vascular Wall-Resident Multipotent Stem Cells within the Process of Vascular Remodelling
3 Implications of MicroRNAs in the Vascular Homeostasis and Remodeling
4 Lifestyle and Aging Effects in the Development of Insulin Resistance — Activating the Muscle as Strategy Against Insulin Resistance by Modulating Cytokines and HSP70
5 Importance of Plasma Membrane Nanodomains in Skeletal Muscle Regeneration
6 Molecular Mechanisms Controlling Skeletal Muscle Mass
7 Autophagy, a Highly Regulated Intracellular System Essential to Skeletal Muscle Homeostasis — Role in Disease, Exercise and Altitude Exposure
8 Cell Composition of the Subendothelial Aortic Intima and the Role of Alpha-Smooth Muscle Actin Expressing Pericyte-Like Cells and Smooth Muscle Cells in the Development of Atherosclerosis
9 Dynamic Interplay Between Smooth Muscle Cells and Macrophages in Vascular Disease
10 Current Challenges in Understanding the Story of Skin Pigmentation — Bridging the Morpho-Anatomical and Functional Aspects of Mammalian Melanocytes
11 Ca2+ Dynamics and Ca2+ Sensitization in the Regulation of Airway Smooth Muscle Tone
12 Research on Skeletal Muscle Diseases Using Pluripotent Stem Cells
13 Smooth Muscle and Extracellular Matrix Interactions in Health and Disease
14 Novel Therapeutic Approaches for Skeletal Muscle Dystrophies
15 Use of Biomaterials and Biomolecules for the Prevention of Restenosis
16 Three-Dimensional “Honeycomb” Culture System that Helps to Maintain the Contractile Phenotype of Vascular Smooth Muscle Cells
17 Role of Platelet-Activating Factor and Hypoxia in Persistent Pulmonary Hypertension of the Newborn — Studies with Perinatal Pulmonary Vascular Smooth Muscle Cells