"Breast Cancer: From Biology to Medicine" ed. by Phuc Van Pham

This volume thoroughly examines breast cancer from basic definitions, to cellular and molecular biology, to diagnosis and treatment. This book also has some additional focus on preclinical and clinical results in diagnosis and treatment of breast cancer.

The book begins with introduction on epidemiology and pathophysiology of breast cancer in Section 1.
In Section 2, the subsequent chapters introduce molecular and cellular biology of breast cancer with some particular signaling pathways, the gene expression, as well as the gene methylation and genomic imprinting, especially the existence of breast cancer stem cells. In Section 3, some new diagnostic methods and updated therapies from surgery, chemotherapy, hormone therapy, immunotherapy, radiotherapy, and some complementary therapies are discussed.
This book provides a succinct yet comprehensive overview of breast cancer for advanced students, graduate students, and researchers as well as those working with breast cancer in a clinical setting.


Contents
Preface
1 Epidemiology, Pathology, Management and Open Challenges of Breast Cancer in Central Sudan: A Prototypical Limited Resource African Setting
2 Histopathological Characteristics: Clinical Course of Breast Cancer Subtypes Depending on the ER(+) (−)/PR(+) (−) Receptor Status
3 Breast Cancer as an Epstein-Barr Virus (EBV)-Associated Malignancy
4 Early-Stage Progression of Breast Cancer
5 GWAS in Breast Cancer
6 Circulating Tumor Cells in Breast Cancer: A Potential Liquid Biopsy
7 DNA Hypermethylation in Breast Cancer
8 ErbB2 Receptor in Breast Cancer: Implications in Cancer Cell Migration, Invasion and Resistance to Targeted Therapy
9 Analysis of 10086 Microarray Gene Expression Data Uncovers Genes that Subclassify Breast Cancer Intrinsic Subtypes
10 Jab1/Csn5 Signaling in Breast Cancer
11 Splicing Factors in Breast Cancer: Drivers of the Breast Tumor Fate
12 The Role of Stem Cells in Breast Cancer
13 Ion Channels in Breast Cancer: From Signaling to Therapy
14 Modern Radiotherapy Era in Breast Cancer
15 Breast Cancer and Flavonoids as Treatment Strategy
16 Translational Challenges and Therapeutic Opportunities in BRCA1-Related Breast Cancer
17 Molecular Fingerprints and Biomarkers of Breast Cancer
18 Cardiac Toxicity of HER2-Directed Therapy in Women with Breast Cancer: Epidemiology, Etiology, Risk Factors, and Management
19 Aspects of Immediate and Delayed Alloplastic Breast Reconstruction After Mastectomy
20 Internal Mammary Sentinel Lymph Node Biopsy
21 Nanobiotechnology for Breast Cancer Treatment
22 Immunotherapeutic and Preventive Role of Purified Extract Rich in Beta-Glucans Derived from D-Fraction of Grifola frondosa Mushroom in Experimental Mice Biomodel of Mammary Carcinogenesis
23 Breast Cancer: From Transcriptional Control to Clinical Outcome
24 Immune Regulation in Breast Cancer Metastasis and Immunotherapy
25 Felt Needs for Rehabilitation After Breast Cancer Treatment in Mexico
26 Naringenin Inhibits Proliferation and Survival of Tamoxifen‐ Resistant Breast Cancer Cells