A Beginner'S Guide To Gene Editing

Explore the gene editing tools - ZFN, TALEN, CRISPR Cas and their extensive applications

What you'll learn
You'll get a bird's eye view of gene editing technologies- ZFN, TALEN and CRISPR Cas and current advances in the field
You'll discover examples of novel applications of gene editing using CRISPR Cas system
Compare and contrast ZFN, TALEN and CRISPR Cas gene editing tools and learn where they are usually applied
You'll learn about the ethical aspects related to germline gene editing
You'll learn how newer technologies emerged from the original CRISPR Cas system
Requirements
Basic knowledge in molecular biology and an understanding of the concepts on DNA replication, repair is required.
Description
This course introduces to you, the enormous possibilities that have been opened up by various gene editing tools developed in the last decade.  You'll learn about Zinc Finger Nucleases, Transcription Activator Like Effector Nucleases, and CRISPR Cas with a special emphasis on the CRISPR Cas system.You'll explore concepts like- Base editing, Prime editing, Mitochondrial Gene editing and much more. Finally you'll study the ethical aspects of gene editing with an interesting case study.The highlights of this lecture series are (i) glimpses into the history and evolution of gene editing nucleases (ii) insights on how fine tuning of the CRISPR Cas system  maximized it's potential in general and clinical applications(iii) discovering  how the same gene editing tool can serve opposite ends of the spectrum of life- revival vs extinction of a species. The course wraps up with a final note on how far this technology can be stretched and how as a researcher you could contribute to this technology and address some of the critical research problems that we are facing today.As is with any course, this course is also backed by Udemy's 30 day money back guarantee.If you're not happy for any reason you will get a full refund.So take this course today, and dive deeper into Gene Editing technologies.

Overview

Section 1: What will you learn

Lecture 1 Introduction

Lecture 2 History of Gene editing

Lecture 3 Which 2 Ideas revolutionized gene editing

Lecture 4 Gene editing Basics

Section 2: Tools for DNA editing

Lecture 5 Zinc finger nucleases

Lecture 6 TALENs

Lecture 7 CRISPR/Cas

Section 3: Applications

Lecture 8 General applications

Lecture 9 Clinical applications

Section 4: Editing the mitochondrial genome

Lecture 10 Mitochondrial Gene editing

Section 5: Ethics

Lecture 11 Ethics in Gene editing

Section 6: New technologies with CRISPR Cas

Lecture 12 Advances in Gene editing technologies

Section 7: Special applications

Lecture 13 Double Edge Sword

Lecture 14 Hacking Mendelian inheritance

Lecture 15 Revival of extinct species

Section 8: Wrap Up

Lecture 16 Summary

Lecture 17 BONUS

This course is suitable for students and researchers pursuing biotechnology and allied disciplines who want to gain insights about gene editing.,This course is not for absolute beginners who are looking for a typical college like curriculum and also not for experts in the field who are looking for advanced knowledge .